Thermo Fisher Scientific SYCN Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SYCN (NP_001073937.1, 1 a.a. approximately 134 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Syncollin,uniProtId:Q0VAF6-1,ncbiNodeId:9606,antigenRange:1-134,antigenLength:134,antigenImageFileName:H00342898-D01P_Syncollin_Q0VAF6-1_Rabbit.svg,antigenImageFileNamePDP:H00342898-D01P_Syncollin_Q0VAF6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MSPLRPLLLA LALASVPCAQ GACPASADLK HSDGTRTCAK LYDKSDPYYE NCCGGAELSL ESGADLPYLP SNWANTASSL VVAPRCELTV WSRQGKAGKT HKFSAGTYPR LEEYRRGILG DWSNAISALY CRCS

Target Information

Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds. Syncollin is also known to associate with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin helps in exocytosis and also plays a role in maturation and/or concentration of zymogens in zymogen granules. Reports suggest that syncollin may also have a pore-forming activity on membranes and regulate exocytosis insome exocrine tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.