Thermo Fisher Scientific SYCN Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody targeting human Syncollin (SYCN) protein. Validated for Western blot applications. Affinity-purified, unconjugated liquid form in PBS buffer. Ideal for studying exocytosis and zymogen granule membrane biology.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SYCN (NP_001073937.1, 1 a.a. ~ 134 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSPLRPLLLA LALASVPCAQ GACPASADLK HSDGTRTCAK LYDKSDPYYE NCCGGAELSL ESGADLPYLP SNWANTASSL VVAPRCELTV WSRQGKAGKT HKFSAGTYPR LEEYRRGILG DWSNAISALY CRCS
Target Information
Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds and associates with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin helps in exocytosis and plays a role in maturation and/or concentration of zymogens in zymogen granules. Reports suggest that syncollin may also have pore-forming activity on membranes and regulate exocytosis in some exocrine tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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