Thermo Fisher Scientific CRP Polyclonal Antibody
Thermo Fisher Scientific의 CRP Polyclonal Antibody는 인간 CRP 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot과 IHC에 적합하며, 동결건조 형태로 제공됩니다. 염증 반응 연구 및 면역학적 분석에 활용 가능합니다.
- 카탈로그번호
- OSC00208W-100UL
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human C Reactive Protein (CRP) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CRP.
Target Information
CRP (C-reactive protein) is a major cyclic, pentameric acute-phase protein consisting of five identical, noncovalently bound, nonglycosylated subunits. Each subunit is composed of 206 amino acids with a molecular weight of approximately 24 kDa.
CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes. It initiates the classical complement cascade, binds nuclear components (chromatin, histones, etc.), and plays a crucial role in innate immunity.
CRP levels can increase 100–1000 fold in response to injury, infection, or inflammation. It acts as an opsonin, activates monocytes/macrophages, and binds nuclear components such as chromatin and snRNP, suggesting a scavenger role during cell necrosis.
Elevated CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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