
Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI1G10), TrueMAB
Human CTLA4 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:500 희석으로 사용 가능. Lyophilized 형태이며, PBS 및 trehalose buffer에 보존. 세포 표면 CTLA4의 연구용 검출에 적합. Research Use Only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G10 |
| Immunogen | Full length human recombinant protein of human CTLA4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve ~1 mg/mL concentration.
- For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells. It binds CD80 and CD86 with higher affinity than CD28, inhibiting T cell activation. Intracellular CTLA4 is also found in regulatory T cells and contributes to their suppressive function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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