Thermo Fisher Scientific STK11 Monoclonal Antibody (OTI1F10), TrueMAB
인간 STK11 단백질을 타깃으로 한 마우스 단클론 항체. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. PBS 버퍼에 8% 트레할로스 포함, 방부제 무첨가. 암 연구 및 단백질 인산화 조절 연구에 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–236 of human STK11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
LKB1 (STK11) is a serine/threonine-protein kinase and tumor suppressor. It interacts with p53 and regulates p53-dependent apoptosis pathways. LKB1 localizes to both cytoplasm and nucleus and translocates to mitochondria during apoptosis. It acts as a master upstream kinase regulating AMPK and related kinases. Mutations in the LKB1 gene are associated with Peutz–Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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