
Thermo Fisher Scientific Caspase-1 p20 Polyclonal Antibody
Caspase-1 p20 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. WB, IHC, ICC, Flow Cytometry, ELISA 등 다양한 실험에 사용 가능하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse Caspase-1 p20 (amino acids 181–280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01 M TBS, pH 7.4, with 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Caspase-1 (CASP1) is a thiol protease that cleaves IL-1β between Asp and Ala, releasing the mature cytokine involved in inflammatory processes. CASP1 plays a key role in pathogen defense, activates sterol regulatory element-binding proteins (SREBPs), and promotes apoptosis. Upon inflammasome activation during DNA virus infection, CASP1 regulates antiviral immunity through cleavage and inactivation of CGAS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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