Thermo Fisher Scientific MAP2K4 Monoclonal Antibody (2D10D8, 4G11B2, 2D10C4, 2D10C3)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

2D10D8, 4G11B2, 2D10C4, 2D10C3

Immunogen

Purified recombinant fragment of MAP2K4 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10979277

Product Specific Information

MA5-15308 targets MAP2K4 in indirect ELISA, IHC applications and shows reactivity with Human samples.

The MA5-15308 immunogen is purified recombinant fragment of MAP2K4 expressed in E. Coli.

Target Information

MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38. MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs. MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.