
Thermo Fisher Scientific ELK1 Monoclonal Antibody (3H6D12, 4H9C8, 4H9F1)
인간 ELK1 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체로, WB, IHC, ELISA에 적합합니다. 비결합형 액상 형태이며 4°C 또는 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H6D12, 4H9C8, 4H9F1 |
| Immunogen | Purified recombinant fragment of ELK1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10978011 |
Product Specific Information
MA5-15310 targets ELK1 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen used is a purified recombinant fragment of ELK1 expressed in E. coli.
Target Information
ELK1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors.
It is phosphorylated by MAP kinase pathways at a cluster of serine/threonine motifs at its C-terminus, with phosphorylation at Ser383 being critical for transcriptional activation.
ELK1 serves as a direct target of activated MAP kinase and acts as a nuclear target for the Ras-Raf-MAPK signaling cascade.
Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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