
Thermo Fisher Scientific BCoR Polyclonal Antibody
BCoR 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 연구용으로 4°C에서 보관.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of human BCL6 co-repressor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Transcriptional corepressor that may specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated in part by histone deacetylase activities associated with this corepressor.
Involved in repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Through repression of TFAP2A, acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, implying inhibition of methylation on histone H3 Lys-4 (H3K4me3) and Lys-36 (H3K36me2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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