Thermo Fisher Scientific POMK Monoclonal Antibody (OTI2B10)
Thermo Fisher Scientific의 POMK 단클론 항체(OTI2B10)는 인간 POMK 단백질에 특이적으로 반응하는 Mouse IgG1 형 항체입니다. Western blot 및 IHC(Paraffin) 응용에 적합하며, 고순도 Affinity Chromatography 방식으로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 141–350 of SGK196 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725068 |
Target Information
This gene encodes a protein involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (α-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: MA5-26678_POMK_Q9H5K3-1_House_mouse.svg, MA5-26678_POMK_Q9H5K3-1_House_mouse_PDP.jpeg)
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