Thermo Fisher Scientific KIF1C/LTXS1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human KIF1C/LTXS1, validated for WB and IP. Targets residues 1000–1050 of KIF1C. Supplied as liquid at 0.2 mg/mL, stored at 4°C. Suitable for studying kinesin-mediated transport and cell division mechanisms.
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- A301071Ax (2개 옵션)
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- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific KIF1C/LTXS1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1000 and 1050 of human kinesin family member 1C (lethal toxin sensitivity 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The kinesins constitute a large family of microtubule-dependent motor proteins responsible for the distribution of organelles, vesicles, and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events such as endocytosis and transcytosis.
KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins involved in the transport of mitochondria or synaptic vesicles in axons. Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein abundantly expressed in heart and skeletal muscle. Tyrosine phosphorylation is a putative regulator of KIF1C-mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C can form homodimers and noncovalently associate with 14-3-3 beta, gamma, epsilon, and zeta. In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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