원본
Thermo Fisher Scientific Nucleolar protein 3 Polyclonal Antibody
상품 한눈에 보기
ARC(NOL3) 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Rabbit IgG 기반, Protein A 정제, 고순도 액상 형태. 세포사멸 억제 관련 연구용으로 사용.
- 카탈로그번호
- BS-7080R
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다회원가입 없이 바로 구매하세요
가입하지 않아도 비회원가로 구매하실 수 있습니다.
마지막 업데이트 2025. 08. 04. 오후 06:41
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific BS-7080R Nucleolar protein 3 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
531,800원VAT 포함 584,980원
Thermo Fisher Scientific · Thermo Fisher Scientific Nucleolar protein 3 Polyclonal Antibody
Thermo Fisher Scientific Nucleolar protein 3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse Nucleolar protein 3 / Apoptosis repressor with CARD, amino acids 1–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ARC (also known as NOL3 - Nucleolar protein 3) has two isoforms:
- Isoform 1 is involved in RNA splicing.
- Isoform 2 functions as an apoptosis repressor that blocks multiple modes of cell death.
ARC inhibits extrinsic apoptotic pathways by:
- Interacting with FAS and FADD upon FAS activation, blocking death-inducing signaling complex (DISC) assembly.
- Interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner, limiting soluble CASP8 available for DISC-mediated activation.
ARC also inhibits intrinsic apoptotic pathways through interactions with BAX, resulting in BAX inactivation and prevention of mitochondrial dysfunction and release of pro-apoptotic factors.
Mutations affecting this gene can result in myoclonus and familial cortical disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
Thermo Fisher ScientificThermo Fisher Scientific CDC2L6 Polyclonal Antibody531,800원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific GADD45 gamma Polyclonal Antibody551,400원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific RERE Polyclonal Antibody531,800원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific Noxa Polyclonal Antibody531,800원VAT별도
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.