Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI8F1), TrueMAB
인간 CTLA4 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Flow cytometry에 사용 가능. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 연구용으로 세포 면역 조절 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F1 |
| Immunogen | Full length human recombinant protein of human CTLA4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells. It binds CD80 and CD86 on B cells and dendritic cells with higher affinity than CD28. Unlike CD28, CTLA4 inhibits T cell activation and function. Intracellular CTLA4 is also found in regulatory T cells and contributes to their immunomodulatory role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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