Thermo Fisher Scientific GKN1 Polyclonal Antibody
Thermo Fisher Scientific의 GKN1 Polyclonal Antibody는 마우스 시료에 반응하는 Rabbit IgG 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 인간 GKN1 단백질(aa 25-185)을 면역원으로 사용하며, 위점막 관련 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25–185 of human GKN1 (NP_0625633) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2805276 |
Product Specific Information
Immunogen sequence:
LGVFLAPALA NYNINVNDDN NNAGSGQQSV SVNNEHNVAN VDNNNGWDSW NSIWDYGNGF AATRLFQKKT CIVHKMNKEV MPSIQSLDAL VKEKKLQGKG PGGPPPKGLM YSVNPNKVDD LSKFGKNIAN MCRGIPTYMA EEMQEASLFF YSGTCYTTSV L
Positive Samples: Mouse stomach
Target Information
Gastrokine 1 (GKN1), also known as CA11, is a 185-amino-acid secreted protein belonging to the gastrokine family, characterized by a BRICHOS domain and an asn-rich region. GKN1 functions as an antioncogene and is down-regulated in human gastric cancer tissues compared to normal gastric mucosa. It is predominantly expressed in the stomach and co-secreted with mucins, acting as a signaling growth factor with mitogenic activity, potentially involved in maintaining gastric mucosal integrity.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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