Thermo Fisher Scientific GPM6A Polyclonal Antibody
GPM6A 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체. 인간, 마우스, 랫트 반응성 확인됨. WB 및 IHC(P) 응용에 적합. 액상 형태로 제공되며 0.5 mg/mL 농도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific GPM6A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QTYFEMARTAGD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933284 |
Product Specific Information
- Expected to recognize all reported isoforms (NP_005268.1; NP_963885.1; NP_963886.1)
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000
- Not recommended for ICC/IF
Target Information
Neuronal membrane glycoprotein M6-a is a protein encoded by the GPM6A gene in humans.
It is involved in neuronal differentiation, including differentiation and migration of neuronal stem cells.
Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility, and synapse formation.
GPM6A-induced filopodia formation involves MAPK and Src signaling pathways.
May participate in neuronal NGF-dependent Ca²⁺ influx and regulation of endocytosis and intracellular trafficking of GPCRs, enhancing internalization and recycling of mu-type opioid receptor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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