Thermo Fisher Scientific TIAM2 Polyclonal Antibody
Human TIAM2 단백질을 인식하는 Goat Polyclonal Antibody로, IHC(P) 등에 사용 가능. TLQGSKNHSNT-C 펩타이드(aa 9-19)를 면역원으로 제작. 0.5 mg/mL 농도의 액상 형태, TBS(pH 7.3, 0.5% BSA) 버퍼에 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence TLQGSKNHSNT-C (aa 9–19) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933285 |
Product Specific Information
- This antibody is expected to recognize isoform a (NP_036586.2) only.
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
TIAM2 modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities.
Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them.
Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth.
Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons.
Promotes migration of neurons in the cerebral cortex.
When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane.
Activates specifically RAC1, but not CDC42 and RHOA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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