Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장 가능.
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Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 400–600 µg extracts |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 222–313 of human Synaptophysin (NP_003170.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.79 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914561 |
Product Specific Information
Positive test controls include SH-SY5Y, Mouse lung, Mouse kidney, and Rat lung.
The target is typically localized to cell junctions, cytoplasmic vesicles, multi-pass membrane proteins, secretory vesicles, synapses, synaptic vesicle membranes, and synaptosomes.
Immunogen sequence:
VFKETGWAAP FLRAPPGAPE KQPAPGDAYG DAGYGQGPGG YGPQDSYGPQ GGYQPDYGQP AGSGGSGYGP QGDYGQQGYG PQGAPTSFSN QM
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, indicating a role in synaptic vesicle endocytosis. It also regulates short-term and long-term synaptic plasticity and serves as a widely used marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene can lead to X-linked mental retardation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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(이미지: PA5-120989_Synaptophysin_P08247-1_Rabbit.svg, PA5-120989_Synaptophysin_P08247-1_Rabbit_PDP.jpeg)
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