Thermo Fisher Scientific KIR2DL2 Polyclonal Antibody
KIR2DL2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 적합하며, 인간 및 생쥐 시료에서 내인성 KIR2DL2를 검출. 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol 저장용액으로 제공.
- 카탈로그번호
- PA5103908
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:1,000–1:3,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIR2DL2 (Accession P43627), corresponding to amino acid residues T146–Y196 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853240 |
Product Specific Information
This antibody detects endogenous levels of total KIR2DL2.
Target Information
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer (NK) cells and subsets of T cells. The KIR genes are polymorphic and highly homologous, located on chromosome 19q13.4 within the leukocyte receptor complex (LRC).
KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by the length of their cytoplasmic domain (L or S).
- Long (L) cytoplasmic domain: Transduces inhibitory signals via ITIM motifs
- Short (S) cytoplasmic domain: Associates with TYRO protein tyrosine kinase binding protein to transduce activating signals
Ligands for several KIR proteins are subsets of HLA class I molecules, indicating their role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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