Thermo Fisher Scientific ICAM-5 Precursor Polyclonal Antibody
ICAM-5 단백질을 인식하는 토끼 폴리클로날 항체로, 인간, 생쥐, 랫드, 영장류 시료에 반응합니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. 신경세포 간 접착 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ICAM5 (Accession Q9UMF0), corresponding to amino acid residues G889–A924 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853238 |
Product Specific Information
This antibody detects endogenous levels of total ICAM5.
Target Information
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. ICAM proteins are type I transmembrane glycoproteins containing 2–9 immunoglobulin-like C2-type domains and bind to the leukocyte adhesion LFA-1 protein. ICAM-5 is expressed on the surface of telencephalic neurons and mediates both homophilic (neuron-neuron) and heterophilic (neuron-leukocyte) adhesion. It may play a critical role in neuron–microglial interactions during normal development or in neurodegenerative processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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