Thermo Fisher Scientific VPS37A Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 VPS37A 폴리클로날 항체. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로 안정적인 액상 형태 제공. 장기 보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human VPS37A. Recombinant protein control fragment (Product #RP-93841). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649464 |
Product Specific Information
Immunogen sequence:
DVPDAFPELS ELSVSQLTDM NEQEEVLLEQ FLTLPQLKQI ITDKDDLVKS IEELARKNLL LEPSLEAKRQ TVLDKYELLT QMKSTF
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
This gene belongs to the VPS37 family and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, which is required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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