Thermo Fisher Scientific ASCC1 Monoclonal Antibody (OTI1E2), TrueMAB
ASCC1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, Flow Cytometry에 사용 가능. HEK293T 세포에서 발현된 full-length human ASCC1 항원을 면역원으로 사용. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E2 |
| Immunogen | Full length human recombinant protein of human ASCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex.
The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB), and serum response factor (SRF).
The encoded protein contains an N-terminal KH-type RNA-binding motif required for AP-1 transactivation by the ASC-1 complex.
Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.
Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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