Thermo Fisher Scientific RND1 Monoclonal Antibody (OTI1C3), TrueMAB
RND1 단백질을 인식하는 Mouse monoclonal 항체로, WB, ICC/IF, Flow Cytometry에 적합합니다. HEK293T 세포에서 발현된 full-length human RND1 단백질로 면역화되었습니다. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C3 |
| Immunogen | Full length human recombinant protein of human RND1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RND1 lacks intrinsic GTPase activity and constitutively binds GTP. It regulates actin cytoskeleton rearrangement and induces Rac-dependent neuritic process formation by disrupting cortical actin filaments. This leads to the formation of multiple neuritic processes from the cell body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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