Thermo Fisher Scientific IFNAR1 Monoclonal Antibody (C7)
Human IFNAR1 단백질을 인식하는 Mouse monoclonal antibody (Clone C7). Western blot에 최적화되어 있으며, 고순도의 Protein A/G 정제 및 1 mg/mL 농도로 제공. PBS와 50% glycerol에 보관되며, -20°C에서 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C7 |
| Immunogen | Recombinant protein Interferon Alpha/Beta Receptor 1 (amino acids 28–227 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899091 |
Target Information
Interferons are widely used therapeutic agents because of their anti-tumor and antiviral effects, as well as their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines exert their effects by binding to the Type 1 Interferon Receptor (IFNAR1). Downregulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling, which is thought to be influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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