Thermo Fisher Scientific CD205 Polyclonal Antibody
CD205 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human 및 Mouse 시료에 반응하며, 항원 특이적 친화 크로마토그래피로 정제됨. PBS/glycerol 완충액에 보관되며, 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LY75 (Accession O60449), corresponding to amino acid residues L466–K516 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854487 |
Product Specific Information
This antibody detects endogenous levels of total LY75.
Target Information
CD205 (also known as LY75 or Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking, and presentation that enhances antigen-specific T cell immunity.
CD205 is highly expressed by CD8+ dendritic cells and is also found in bone marrow Gr1+ cells, Langerhans cells, bone marrow-derived dendritic cells (BMDC), and thymic epithelial cells.
It functions as an endocytic receptor that directs captured antigens to specialized antigen-processing regions and can modulate B lymphocyte proliferation.
Dysfunction of CD205 has been associated with pneumonic plague and lipid pneumonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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