Thermo Fisher Scientific ATG4A Polyclonal Antibody
ATG4A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 시료 반응성. 고순도의 Affinity chromatography 정제 항체로, PBS/glycerol buffer에 보관. 연구용으로 세포 자가포식 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ATG4A (Accession Q8WYN0), corresponding to amino acid residues K42–C92 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852358 |
Product Specific Information
Antibody detects endogenous levels of total ATG4A.
Target Information
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. It is essential for cell homeostasis and remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been observed in some malignant tumors, and it may play a role in regulating uncontrolled cell growth associated with cancer.
This gene encodes a member of the autophagin protein family, also known as a member of the C-54 family of cysteine proteases. Transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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