Thermo Fisher Scientific CYP1A2 Polyclonal Antibody
CYP1A2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot에 적합하며 인간, 마우스, 랫트 시료에서 반응. 비결합형 액상 형태로 0.5 mg/mL 농도. CYP1A1과 교차 반응하지 않음.
- 카탈로그번호
- PA5142817
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HSENYKDNGGLIPEEK (aa 289–304) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933460 |
Product Specific Information
- This antibody is not expected to cross-react with the similar P450 1A1.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
The CYP1A2 gene encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and its expression is induced by polycyclic aromatic hydrocarbons (PAHs), including those found in cigarette smoke.
Although the enzyme’s endogenous substrate is unknown, it can metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates include caffeine, aflatoxin B1, and acetaminophen. The transcript contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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