Thermo Fisher Scientific Phospho-eIF2 beta (Ser2) Polyclonal Antibody
Phospho-eIF2 beta (Ser2) 항체로, 인산화된 EIF2S2 단백질의 Ser2 잔기를 특이적으로 인식합니다. Western blot 및 IHC(P) 실험에 적합하며, 사람, 생쥐, 랫트 시료에서 반응합니다. 고순도 정제 및 안정적 PBS/glycerol buffer로 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF2S2 (Accession P20042), corresponding to amino acid residues around phosphorylated Ser2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817568 |
Product Specific Information
This antibody detects endogenous levels of EIF2S2 only when phosphorylated at Ser2.
Target Information
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits—alpha, beta, and gamma—with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, recycling the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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