Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Calreticulin 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 종에 반응. WB, IHC, ICC 등 여러 응용 분야에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
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Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| Neutralization (Neu) | Assay-dependent |
| Dot Blot (DB) | Assay-dependent |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Hamster, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A fusion protein to mouse calreticulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2069604 |
Product Specific Information
Suggested positive control: antigen standard for CALR (transient overexpression lysate).
Target Information
Calr (Calreticulin) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all monoglucosylated glycoproteins synthesized in the ER. It also interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Calr may play a role in maternal gene expression regulation and oocyte maturation through calcium homeostasis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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