Thermo Fisher Scientific HB-EGF Polyclonal Antibody
HB-EGF 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도. -20°C 보관, 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human HB-EGF/DTSF, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HBEGF (Heparin-binding EGF-like growth factor) is a growth factor that mediates its effects via EGFR, ERBB2, and ERBB4. It is essential for normal cardiac valve formation and heart function. HBEGF promotes smooth muscle cell proliferation and may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts but not endothelial cells. HBEGF binds to the EGF receptor with higher affinity than EGF itself and is a more potent mitogen for smooth muscle cells. It also acts as a diphtheria toxin receptor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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