Thermo Fisher Scientific DNAJB4 Polyclonal Antibody
Thermo Fisher Scientific DNAJB4 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot 및 IHC(P)에 사용 가능. 합성 펩타이드(aa 90–132)를 면역원으로 제작된 고순도 항체로, 38 kDa 단백질 검출에 적합. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: -
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 90–132 of human DnaJB4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553507 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 38 kDa.
- Purity >95% by SDS-PAGE.
Target Information
DnaJ heat shock induced proteins originate from Escherichia coli and are regulated by the htpR protein. These proteins play a key role in the HSP70 chaperone machinery by interacting with HSP70 to stimulate ATP hydrolysis. They contain cysteine-rich zinc finger regions forming peptide-binding domains responsible for chaperone function. DnaJ proteins mediate proteolysis and regulate protein degradation, exocytosis, and endocytosis.
DnaJB4 (DnaJ homolog subfamily B member 4), also known as HLJ1, is expressed in skeletal muscle, heart, and pancreas, with lower expression in brain, placenta, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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