Thermo Fisher Scientific FANCL Polyclonal Antibody
인간 FANCL 단백질을 인식하는 Rabbit Polyclonal 항체입니다. IHC(P)에서 1:200–1:500 희석으로 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Tested Applications and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FANCL. Recombinant protein control fragment (Product #RP-96016) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641500 |
Product Specific Information
Immunogen sequence:
FPARAILEKS DFTMDCGICY AYQLDGTIPD QVCDNSQCGQ PFHQICLYEW LRGLLTSRQS FNIIFGECPY CSKPIT
Sequence identity to orthologs:
- Mouse: 82%
- Rat: 80%
Target Information
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM, and FANCN (also called PALB2).
The previously defined group FANCH is the same as FANCA.
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex.
This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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