Thermo Fisher Scientific FANCL Polyclonal Antibody
Rabbit polyclonal antibody against human FANCL protein. Validated for WB, IHC (Paraffin), and ICC/IF applications. Provides high specificity and affinity through antigen affinity chromatography purification. Suitable for research use only.
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- PA557768
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | — |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | — |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FANCL. Recombinant protein control fragment (Product # RP-96017) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641499 |
Product Specific Information
Immunogen sequence:
ALKNRQELYA LPPPPQFYSS LIEEIGTLGW DKLVYADTCF STIKLKAEDA SGREHLITLK LKAKYPAESP DYFVDFPVPF C
Highest antigen sequence identity:
- Mouse: 65%
- Rat: 67%
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
Members of the FANC group are related by their assembly into a common nuclear protein complex.
This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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