Thermo Fisher Scientific IRX5 Monoclonal Antibody (8A12)
IRX5 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot, ICC/IF, ELISA 등 다양한 응용 가능. 인간 및 생쥐 반응성. 액상 형태로 제공되며 PBS buffer에 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A12 |
| Immunogen | IRX5 (NP_005844, 204–264 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
PQKPEDKADP EGPEAGGAEQ KAASGCERLQ GPPTPAGKET EGSLSDSDFK EPPSEGRLDA L
Target Information
IRX5 establishes the cardiac repolarization gradient by repressing the KCND2 potassium-channel gene.
It is required for retinal cone bipolar cell differentiation and may regulate contrast adaptation and visual function in mammalian retina circuits.
IRX5 could be involved in the regulation of cell cycle and apoptosis in prostate cancer cells, as well as in craniofacial and gonadal development.
It modulates migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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