Thermo Fisher Scientific GNAO1 Polyclonal Antibody
Thermo Fisher Scientific의 GNAO1 폴리클로날 항체로, 인간 GNAO1 단백질을 인식합니다. Western blot 및 면역조직화학(IHC) 적용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 높은 종 간 보존성을 가지며 연구용으로 적합합니다.
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- PA559337
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카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC-F) | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GNAO1. Recombinant protein control fragment (Product #RP-102901). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642080 |
Product Specific Information
Immunogen sequence:
IQSLAAIVRA MDTLGIEYGD KERKADAKMV CDVVSRMEDT EPFSAELLSA MMRLWGDSGI QECF
Sequence identity with orthologs:
- Mouse: 95%
- Rat: 97%
Target Information
Heterotrimeric G proteins are membrane-bound GTPases linked to 7-transmembrane receptors. Each G protein consists of alpha, beta, and gamma subunits and is bound to GDP in the "off" state. Ligand-receptor binding activates the G protein, switching it to the "on" state and enabling Galpha-mediated second messenger signaling cascades.
Galpha proteins regulate adenylyl cyclase activity, modulating intracellular cAMP levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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