Thermo Fisher Scientific eIF6 Polyclonal Antibody
Thermo Fisher Scientific의 eIF6 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot, IHC, ICC에 적합합니다. 항원 친화 크로마토그래피로 정제된 비접합 항체로, 장기 보관 시 -20°C에서 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human eIF6. Recombinant protein control fragment (Product #RP-99421). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640979 |
Product Specific Information
Immunogen sequence:
LSALGNVTTC NDYVALVHPD LDRETEEILA DVLKVEVFRQ TVADQVLVGS YCVFSNQGGL VHPKTSIEDQ DELSSLLQVP
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
Hemidesmosomes are structures that link the basal lamina to the intermediate filament cytoskeleton. An important component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), which contains two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found in both the nucleus and cytoplasm, functions as a translation initiation factor and prevents the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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