Thermo Fisher Scientific LAMR1CT Polyclonal Antibody
LAMR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 안정한 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific LAMR1CT Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LAMR1 (amino acids 201–295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Laminins are extracellular matrix glycoproteins and major noncollagenous constituents of basement membranes. They are involved in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Many effects of laminin are mediated through interactions with cell surface receptors, including integrins and non-integrin laminin-binding proteins.
LAMR1 encodes a high-affinity, non-integrin laminin receptor, also known as 67 kD laminin receptor or 37 kD laminin receptor precursor (37LRP). The amino acid sequence of LAMR1 is highly conserved, indicating its essential biological role. Elevated expression has been observed in colon carcinoma and lung cancer cells, correlating with invasive and metastatic phenotypes. Multiple pseudogene copies exist, and two alternatively spliced transcript variants encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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