Thermo Fisher Scientific PTPN21 Polyclonal Antibody
Human PTPN21 단백질을 인식하는 Rabbit Polyclonal Antibody. ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며, 단기 4°C, 장기 -20°C 저장 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PTPN21. Recombinant protein control fragment (Product # RP-108627) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792093 |
Product Specific Information
Immunogen sequence:
KVALLHQKYR GLTAPDAEML YMQEVERMDG YGEESYPAKD SQGSDISIGA CLEGIFVKHK NGRHPVVFRW HDIANMSHNK S
Target Information
The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation, and the mitotic cycle.
PTPN21 (protein tyrosine phosphatase, non-receptor type 21), also known as PTPD1 or PTPRL10, is a 1,174 amino acid member of the PTP family and localizes to both the cytoplasm and the cytoskeleton.
Containing one FERM domain and one tyrosine-protein phosphatase domain, PTPN21 catalyzes the water-dependent conversion of a protein tyrosine phosphate into a protein tyrosine and a free phosphate.
This protein may be involved in liver regeneration and spermatogenesis. The gene encoding PTPN21 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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