Thermo Fisher Scientific PIWIL2 Polyclonal Antibody
PIWIL2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5102687
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PIWIL2 (Accession Q8TC59), corresponding to amino acid residues C791–E841 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852082 |
Product Specific Information
Antibody detects endogenous levels of total PIWIL2.
Target Information
The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes (the piwi or Argonaute family). The Piwi family is required for germ and stem cell development in invertebrates, and two Piwi members, MIWI and MILI (Miwi-like, Piwil2, Piwi-like protein 2), are essential for spermatogenesis in mouse. MIWI and MILI partner with Piwi-interacting RNAs (piRNAs), which are 26–31 nucleotides in length, distinct from microRNAs (miRNAs) or short interfering RNAs (siRNAs). Developmentally regulated piRNA loci have been identified, suggesting MILI plays an important role in meiotic prophase progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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