Thermo Fisher Scientific RASGRF1 Polyclonal Antibody
Human RASGRF1 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RASGRF1. Recombinant protein control fragment (Product # RP-98034) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646333 |
Product Specific Information
Immunogen sequence:
RKLSLNIPII TGGKALDLAA LSCNSNGYTS MYSAMSPFSK ATLDTSKLYV SSSFTNKIPD EGDTTPEKPE DPSALSKQSS EVSMREESDI DQNQSDDGDT E
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 58%
- Rat: 55%
Target Information
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. It stimulates the dissociation of GDP from RAS protein. Studies in mouse suggest that Ras-GEF activity in brain can be activated by Ca²⁺ influx, muscarinic receptors, and G protein βγ subunits. The Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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