Thermo Fisher Scientific VLK Polyclonal Antibody
Rabbit polyclonal antibody against human VLK. Validated for WB and IHC-P applications. Antigen affinity purified and supplied in PBS with 40% glycerol. Recommended storage at 4°C short term or -20°C long term. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:20–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to human VLK. Recombinant protein control fragment (Product #RP-95072) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856327 |
Product Specific Information
Immunogen sequence:
TEYQCIPDST IPQEDYRCWP SYHHGSCLLS VFNLAEAVDV CESHAQCRAF VVTNQTTWTG RQLVFFKTGW SQVVPDPNKT T
Target Information
VLK is a novel protein kinase induced after differentiation of embryonic stem cells into mesendoderm. It is conserved among vertebrates and enriched in the Golgi apparatus, where it may regulate protein export rates. VLK expression transitions from E-cadherin-positive visceral endoderm to E-cadherin-negative mesenchyme. Disruption of VLK in mice results in lung development defects and neonatal lethality. Mutations in VLK may be associated with atopy.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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