Thermo Fisher Scientific ALS2CR2 Polyclonal Antibody
ALS2CR2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF 등에 사용 가능. 인간 및 생쥐 시료 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체이며, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human ALS2CR2. Recombinant protein control fragment (Product #RP-95062). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.30 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856328 |
Product Specific Information
Immunogen sequence:
VPFQDMHRTQ MLLQKLKGPP YSPLDISIFP QSESRMKNSQ SGVDSGIGES VLVSSGTHTV NSDRLHTPSS
Target Information
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11 (a master kinase that regulates cell polarity and energy-generating metabolism).
This complex regulates the relocation of this kinase from the nucleus to the cytoplasm and is essential for G1 cell cycle arrest mediated by this kinase.
The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, enhancing anti-apoptotic activity via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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