Thermo Fisher Scientific Laminin alpha-5 Polyclonal Antibody
Rabbit polyclonal antibody targeting Laminin alpha-5 for extracellular matrix research. Recombinant human antigen immunogen. Provided as liquid, unconjugated form at 0.1 mg/mL. Suitable for tissue development and integrity studies. For research use only.
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- PA565883
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Thermo Fisher Scientific Laminin alpha-5 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Laminin alpha-5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662061 |
Product Specific Information
Immunogen sequence:
QPHTLFVGGLP ASSHSSKLPV TVGFSGCVKR LRLHGRPLGA PTRMAGVTPC ILGPLEAGLF FPGSGGVITL DLPGATLPDV GLELEVRPLA VTGLIFHLG
Highest antigen sequence identity to the following orthologs:
- Mouse: 73%
- Rat: 74%
Target Information
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in organs such as kidney, lung, skin, and nervous system. Laminins mediate cell attachment, migration, and organization into tissues during embryonic development by interacting with other extracellular matrix components.
Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, each representing a different subfamily. The gene encoding Laminin alpha-5 belongs to the alpha subfamily and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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