Thermo Fisher Scientific NDUFB11 Monoclonal Antibody (OTI5B4), TrueMAB
인간 NDUFB11 단백질을 인식하는 단클론 항체로, Western blot에 최적화됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 미토콘드리아 복합체 I 연구용으로 적합하며, 보존제 무첨가 PBS 버퍼에 안정화됨.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 30–163 of human NDUFB11 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NDUFB11 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), not directly involved in catalysis. It functions in electron transfer from NADH to the respiratory chain and is located in the inner mitochondrial membrane. The immediate electron acceptor is believed to be ubiquinone.
NDUFB11 exhibits NADH dehydrogenase and oxidoreductase activities.
Defects in NDUFB11 are associated with linear skin defects with multiple congenital anomalies and mitochondrial complex I deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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