
Thermo Fisher Scientific Phospho-Corticotropin-Releasing Factor Receptor 1 (Thr431) Polyclonal Antibody
인간 CRF1의 Thr431 인산화 부위를 인식하는 폴리클로날 항체. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 액상 형태로 제공되며 4°C 단기 보관, -20°C 장기 보관 권장. 스트레스 반응 및 불안 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CRF1 around the phosphorylation site Thr431 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송/결제/교환/반품 안내
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