Thermo Fisher Scientific ANGPTL7 Monoclonal Antibody (538401)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

8-25 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

538401

Immunogen

CHO-derived recombinant mouse Angiopoietin-like Protein 7/ANGPTL7 Gln22-Pro337 (predicted) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ANGPTL7,uniProtId:Q8R1Q3-1,ncbiNodeId:10090,antigenRange:22-337,antigenLength:337,antigenImageFileName:MA5-24238_ANGPTL7_Q8R1Q3-1_Rat.svg,antigenImageFileNamePDP:MA5-24238_ANGPTL7_Q8R1Q3-1_Rat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606502

Product Specific Information

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Target Information

Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.