Thermo Fisher Scientific PD-L1 Monoclonal Antibody (JC071)
Thermo Fisher Scientific의 PD-L1 Monoclonal Antibody (JC071)는 개 PD-L1에 특이적인 단일클론 항체로, IHC, Flow Cytometry, ELISA 등 다양한 분석에 사용됩니다. 비결합형 액상 포맷이며, Protein A로 정제되어 고순도입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | JC071 |
| Immunogen | Recombinant extracellular domain of canine PD-L1 fused with the Fc domain of human IgG1 expressed in D. melanogaster S2 cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor, programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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