Thermo Fisher Scientific MMACHC Monoclonal Antibody (OTI1B7), TrueMAB
MMACHC 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot과 Flow cytometry에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용. 비보존제 PBS 버퍼에 안정화되어 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B7 |
| Immunogen | Full length human recombinant protein of human MMACHC produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The MMACHC protein’s exact function is not fully understood. Its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. It is postulated that MMACHC may play a role in binding and intracellular trafficking of cobalamin.
Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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