Thermo Fisher Scientific SPR Monoclonal Antibody (4F2)
SPR 단백질을 인식하는 4F2 클론의 마우스 단일클론 항체로, Western blot, ELISA, IP에 사용 가능. 인체 반응성, Affinity chromatography로 정제된 액상형 항체. PBS(pH 7.4) 버퍼, 방부제 없음, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F2 |
| Immunogen | SPR (NP_003115, 164 a.a. ~260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
FKGWALYCAG KAARDMLFQV LALEEPNVRV LNYAPGPLDT DMQQLARETS VDPDMRKGLQ ELKAKGKLVD CKVSAQKLLS LLEKDEFKSG AHVDFYD
Target Information
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4).
Mutations in this gene result in DOPA-responsive dystonia due to sepiapterin reductase deficiency.
A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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