Thermo Fisher Scientific CD11c Monoclonal Antibody (FK24)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:5

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

FK24

Immunogen

AML-blasts

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

PBS with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_1075364

Product Specific Information

The antibody reacts with the alpha chain the 150 kD molecule of the CD11c/CD18 Integrin complex (g150/95) which is expressed on monocytes and in a lower density on granulocytes and NK-cells of peripheral blood. It also reacts with many myelomonocytic and monocytic leukemias and (weakly) with part of the T8 positive cells (OKM1-like). The Integrins are important molecules in cellular adhesion and cellular interactions. Positive controle perifere blood lymphocytes

Target Information

CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.