Thermo Fisher Scientific P2X5 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
TNLIVTPNQRQ NVCAENEGIP DGACSKDSDC HAGEAVTAGN GVKTGRCLRR ENLARGTCEI FAWCPLETSS RPEEPFLKE

Highest antigen sequence identity to the following orthologs:

• Mouse: 74%
• Rat: 74%

Target Information

Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family termed membrane Mg(2+) transporters (MMgTs), which reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable, and studies have shown that Mmgt2 fusion proteins localize to the Golgi complex and post-Golgi vesicles, including early endosomes in COS-7 cells transfected with tagged constructs. Related pathways include transport and binding events such as transport of glucose, bile salts, organic acids, metal ions, and amine compounds.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.