Thermo Fisher Scientific Pirh2 Monoclonal Antibody (1H10)
Pirh2 단백질을 검출하기 위한 Mouse monoclonal antibody로, Human과 Rat 시료에 반응합니다. Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 사용 가능합니다. 정제된 인간 Pirh2 재조합 단백질로부터 유래된 항원으로 제작되었습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H10 |
| Immunogen | Purified recombinant fragment of human Pirh2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10985612 |
Product Specific Information
MA5-15596 targets Pirh2 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and Rat samples.
The immunogen is a purified recombinant fragment of human Pirh2 expressed in E. coli.
MA5-15596 detects Pirh2, which has a predicted molecular weight of approximately 30 kDa; 60 kDa (homodimer).
Target Information
The protein encoded by this gene has ubiquitin-protein ligase activity. It binds with p53 and promotes ubiquitin-mediated proteasomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53, and alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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